Some diabetes medications could make you gain weight. To put it simply, as you get better control of your diabetes, you no longer lose glucose in your urine, so your body retains those calories. Some classes of diabetes drugs are more likely to cause weight gain than others. Sulfonylureas (such as glyburide and glipizide), meglitinides (Prandin), and insulin can cause weight gain. The drugs most commonly associated with weight gain and fluid retention are the thiazolidinediones (glitazones), such as pioglitazone and rosiglitazone. Read more...
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